Abundant stem cells proving to be a cure in hearing loss problem

After many efforts for a number of years by researchers, a major discovery has been made in medical history. Mumbai based ENT doctor, Somali Pandit feels lucky to be a part of this fruitful research. The research says ‘Stem cells would be now used for treating hearing problems’. The research was conducted at Garvan institute of Medical Research in Sydney. Doctor Pandit was doing a thesis at the university and the research was a part of the thesis.

The expert team of Australian university used stem cells which were extracted from the nasal cavity. However, it is still to find out whether stem cells isolated from menstrual blood storage would have given the same results or not. It was not in the knowledge of people of Chembur, Mumbai that a city doctor was a part of this research too. As Pandit says ‘the thesis was being carried out in mice’. The doctor wants to continue research in this field further as further discoveries will lead to elimination of many problems. Adding on to this Doctor Pandit further says that the thesis involved isolation of stem cells from nose. These abundant stem cells were then injected into inner ear or cochlea.

Researchers worked on hearing loss that is caused due to nerve damage. It is also called sensorineural hearing loss which is the most common form of disease these days. According to the research study by Indian council of medical research it was found that about two hundred million Indians suffer from this type of hearing loss. The reason is heavy use of gadgets like mobile phones and iPods. The study used the nasal stem cells rather than stem cells in menstrual blood or adult tissues. The reason quoted by Dr Pandit was that cells extracted from nose can be converted into other cell types. In addition, they are easy to harvest and get replaced constantly.

The research has been published online in the medical journal of stem cells. The researchers’ team found out that stem cells secrete a certain chemical substance that helps in the proper functioning of hearing cells of cochlea. However, the research has yet to be tried on human beings and doctors are positive about its success. Stem cells have the capability to cure a wide number of medical disorders. This is the reason why doctors’ today advice women to store menstrual blood. It is the richest source of stem cells and helps to cure problems that arise in adult and embryonic cells.

Cardiologists using vital stem cells to cure chronic heart problems

One of the most troublesome issues for the researchers and cardiologists today is heart diseases. About a decade ago, the scientists found a solution in stem cells for this problem. These cells are very powerful and keep prowling in the whole body to repair and maintain tissues when required. Scientists can use these vital stem cells and transform them into heart cells in the laboratory. When these are implanted in animals, they can grow into new heart tissue. It further gave rise to a hope among researchers that they can transfuse these stem cells into heart patients. It involves those whose heart has gone weak by heart attacks or those who are not able to pump enough blood through their bodies.

Currently, the number of people suffering from heart diseases is increasing at a great pace including high ratio of baby boomers. Researchers now have come to a conclusion that by using of abundant stem cells, chances to cure heart problems can increase to a large extent. During a heart attack a blockage in the artery cuts off the oxygen supply to the heart that damage billion of cells. In most of the parts, cells do not grow back and thus the region becomes a scar tissue. The circulatory system becomes weak. Many scientists and doctors started extracting stem cells from bone marrow few years back. It showed great compatibility signs. However, the result obtained after the transfusion of bone marrow cells was mixed. The treatment is safe but the improvement was temporary.

The researchers are still practicing on solving this mystery. Recently, it has been discovered that stem cells present in menstrual blood have more potential to differentiate into different cell types. So, there is a high need to preserve menstrual blood as they are highly capable of curing severe heart diseases. Heart attacks are not that deadly as they used to be in past days. A person who has suffered from four or five heart attacks is still alive after a time period of one year. Heart attacks cause damage that results in heart failure and which further reduces the life span of a person.

Dr Eduardo Marban, director of heart institute in Los Angeles began to study stem cells that came from heart instead of bone marrow or menstrual blood bank. These cells called the cardiac progenitor cells repaired heart muscle. The reason was that these transplanted cells secreted chemicals which further improved the functioning of heart and the improvement was not because of growth of any new tissue. The major concern is these cells are very rare. Marban believes that the research is going to reap new results in medical history.

CIT and Stemina Biomarker in partnership for stem cell international based toxicology testing

CIT, a safety and health research laboratory and Stemina Biomarker have made a strategic partnership. CIT is independent, science driven, non clinical CRO (contract research organization). It has its specialization in safety and health research. It carries out numerous projects for companies working abroad. These international companies are working in the field of human and veterinary pharmaceuticals, biotechnology, agrochemicals, chemicals and consumer products. As a result of this partnership CIT will be distributing Stemina’s DevTOX assay in the European market. It will be working for the validation of stem cell international based tests under REACH.

This REACH initiative involves manufacturers and importers to register and then test the chemicals and their composition. DevTOX makes use of human embryonic cells as compared to isolate menstrual blood stem cells. These human embryonic stem cells test chemicals, pharmaceuticals and formulations. These have a negative impact especially on human body and create a toxic effect. This is the reason which causes several birth defects if a woman is exposed to heavy use of chemicals during pregnancy. DevTOX is fully capable to model toxicity during embryo development with ninety percent accuracy level in case of chemicals whose role during human embryo development is known.

Stemina has developed DevTOX by exposing human embryonic cells to a set of drugs like thalidomide. It is used because of the fact that the effect of this drug on the human embryo is known. The effect on the metabolism of the abundant stem cells is analyzed after this. Analysis is done by using proprietary metabolomics platform technology. Human embryonic cells were extracted in the year of 1998 by Dr James Thomson at the Wisconsin University. After its success, the research was later on approved to be used in other developed countries. This research helped to understand embryo development in humans and agents responsible for birth defects on the embryo.

However, the concept of menstrual blood banking is recent and it is being speculated that this discovery will further reveal many new secrets in medical history. Stemina studies responses from hES and other cells derived from them such as heart cells and neurons for drug testing. The company CEO says that they are really very excited with their partnership with CIT in Europe. It is a wonderful achievement for both the companies. The amazing combination of hES cell technology and forty years of experience in toxicology and testing are going to thunder the world. The company’s clients will be able to access most innovative methods of toxicity evaluation and safety of chemicals.

Have a glance on the recent health briefs of vital stem cells

Health is an issue of major concern for people these days. Unacceptable human practices have led to major health problems. This is the reason why people have become highly health conscious. Some of the most interesting health facts of vital stem cells of the week are as follows-

Earlier it was believed that women living on contraceptive pills hold high risk of heart disease. However, according to a new study, it has been found hat there is no link between pills and heart diseases. The revision of medical literature shows that pills do not contain estrogen hormone used in birth control pills. Instead it contains progestin that does not possess any bad impact on heart. The research was conducted on about eighteen hundred women including those who take progestin containing pills. On the other hand, pills help in the regulation of menstrual cycle. Vital menstrual blood is the richest source of stem cells to cure several diseases especially those related to the heart.

A major discovery has been made in medical history which would be very useful for the cancer patients. Researchers of Australian university worked with Indian scientists and created a chemical antibody that can easily find out the cancer stem cells and binds to them only. It is called smart bomb or missile by the researchers. It is composed of a fat particle that has the potential to deliver drugs to the roots of cancerous cells. This results into an effective cancer imaging system which would be useful for the detection of diseases at an early stage. The main reason for increased mortality rate of cancer patients is the inability to detect and eliminate cancerous stem cells further. However, as per recent research it is possible to cure leukemia through stem cells menstrual blood.

According to a study, it has been found out that people need to trust their medication. It is the mindset that decides the duration of diseases. Believing that a particular painkiller will reduce the pain can surely reduce the pain to a great extent.

Barley is must for old age people. Cereal grain can reduce heart diseases and can also be added in soups. It reduces the bad cholesterol level in the body. Similarly, scientists collect menstrual blood to isolate stem cells that is a boon for treatment of heart diseases.

Lemon reduces fats due to pectin present in it that reduces hunger cravings. It has antiviral properties present in its peel. Rubbing a lemon on stings and mosquito bites creates freezing effect. Being rich in anti-oxidants, it reduces the gall stone production.

These are very common but important tips that can prove to be very beneficial most of the times.

United States lacking promising stem cell international therapies

United States is experiencing a lack of potential stem cell therapies these days. A new case has emerged that of Linda Jayaram who was suffering from multiple sclerosis for a period of four decades. The therapy used to involve adult stem cells was not available in USA. The lady decided to go to Israel and got treatment from a university doctor. The therapy was a success and Jayaram showed tremendous improvement after the second infusion. There are several MS patients in America these days who are not satisfied with the kind of treatment available in their own country.

Multiple sclerosis affects central nervous system of patients and its symptoms continue to come and go. Hence, it is assumed that the treatment has worked successfully and requires constant monitoring. The treatments involve the use of stem cells taken from adult tissue that repairs the damaged tissues or revives the immune system. Researchers earlier were not aware of extracting stem cells from menstrual blood which is an abundant source of stem cells. The treatment is being provided in Europe and Asia along with southern part of US border. The reason why this therapy did not get much success in US was the lack of scientific evidence available regarding the success of the therapy.

Only hope is it must show benefits

According to estimates, about 400,000 American residents are suffering from MS today. The cure and the cause of the disease are still not known. Multiple Sclerosis is a disease in which immune system degrades the protective cover present around the nerves and that further affects the communication between brain and body. The lack o communication between the brain and the body gives rise to symptoms like muscle coordination, fatigue, numbness, loss of balance, speech problem, difficulties in bladder and bowels. A few drugs available are only useful if the disease is diagnosed at an early stage. Recently modeled therapy of stem cell international in cancer involves destruction of immune system through chemotherapy. Stem cells injected were isolated from blood before chemo. The newly infected cells reset the immune system to function properly. These days, scientists are also practicing to extract stem cells from menstrual blood storage.

Most exiting discovery

The research has brought about some wonderful miracles. However, the therapy is available in other countries. It is not effective in later stage and also holds high risk for some. In the therapy received by Jayaram there was no chemo involved. Stem cells were taken from bone marrow rather than adult tissue or menstrual blood bank.

US doctors are however concerned that the MS patients go to wrong places sometimes as some clinics do not track patients for improvements later on.

Vital stem cells help women regenerate breasts after cancer surgery

According to a new research, it has been found out that stem cells help to regenerate breasts in women after surgery. The stem cells are basically those undifferentiated cells that are fully capable to differentiate further into other cell types. Till now, surgeons used to collect stem cells from two sources – adult tissue and embryo formed during embryonic development. Recently it has been discovered that menstrual blood is a rich source of stem cells. The researchers have discovered a new cell therapy. This new therapy uses the regenerative capacity of women to grow fat tissues in the breasts.

This amazing technique requires putting a special plastic mould beneath the skin from where the breast has been removed. After this, the region is injected with vital stem cells of the patient. For this, a gel is inserted that helps the cells to multiply. It takes a time period of six months to one year for the fat and stem cells to rejuvenate gradually. This process continues till the new breast tissue is completely formed. Menstrual blood is proving to be the easiest and the richest source for these cells. Moreover, menstrual blood stem cells have the high potential to differentiate into various cells types.

UK and Melbourne scientists have the opinion that the new breasts developed because of this new therapy, make breasts look natural. In addition, it also feels soft on touching. Further, according to the experts the new stem cell therapy is more comfortable and trouble-free as compared to silicon implants. Many researchers are making efforts to make this therapy available to every woman as soon as possible. For this, the targets have already been set and many medical agencies are dedicated to make this discovery known to women all around the world. Women with partial mastectomy, defects due to earlier reconstruction or congenital deformities can also be operated successfully with this wonderful research in the field of medical history.

The therapy is naturally available at premium prices. Professor Kefah Mokbel, a famous breast surgeon consultant at St George’s Hospital of London is successfully conducting this therapy for the past few months. Mokbel has already operated some handful of women patients with abundant stem cells who have started to develop new breasts. According to Mokbel, the results were highly impressive. It is by far the most natural and the most secure method as compared to those that involve insertion of foreign particles. Such type of research was most awaited and several efforts are being made to make this possible. With discovery of this wonderful therapy scientists are hoping to reveal many secrets further.

Thermogenesis agreement with Chinese stem cell international company

Thermogenesis Corp. has signed an agreement for AXP and Bioarchive cord blood systems with Beike. Thermogenesis is the leading supplier of products and services that store adult stem cells. It will supply Beike a stock of AXP and Bioarchive systems for the fiscal year 2011 to be used for processing and stem cells storage. Beike with its headquarters in China provides full range of products obtained from cord blood, umbilical cord tissue and bone marrow cells. It operates three cord blood processing and storage facilities and also eighteen laboratories including cord blood collection, stem cell international research and stem cells banks.

The collaboration between both the organizations will lead to the development of advanced technologies. The approach will further lead to automation of the process for expansion of particular types of stem cells from cord blood. However, menstrual blood stem cells have also the same potential to divide into several other cell types and cure numerous medical disorders just like those obtained from cord blood and umbilical blood. By getting into partnership with Beike, Thermogenesis is hoping to tap the Chinese market which is growing at a high rate in the present day. Their collaboration will aid in the development of the market further. On the other hand, to adopt AXP and Bioarchive technologies is critical for Beike’s strategy to become a leading company in technology and quality services. Further as per company’s CEO AXP implementation is highly critical to become the first bank in China and receive recognition from AABB to process and store cord blood.

Beike biotechnology Co. Ltd

It is among top most biotechnology companies operating in stem cell therapy and stem cell banking. The company’s scientists are dedicated to develop and then commercialize adult stem cells therapies since the year of 1999. The company commenced with its banking operations in the year 2008. Currently, it produces stem cells obtained from umbilical cord, bone marrow and cord blood. Menstrual blood bank being rich and easy source of stem cells can be also used in the near future. The company has published its researches in many publications and journals.

Thermogenesis Corp.

The company manufactures mechanized blood processing systems and products that cannot be used again. Its various products are - AXP device that is used for cord blood processing. Bioarchive is a device used by cord blood banks and collect stem cells for cryopreservation and archiving these cells for transplantation. Others include Res-Q and CryoSeal. The company also has CE-maker for its selling activities throughout Europe.

It is being speculated that the collaboration between the two is naturally going to benefit the Chinese market.

Vital stem cells transplantation: A new hope for person suffering from kidney problems

According to a new study, the scientists have found out that transplantation of RPC’s into rats suffering from kidney damage improved the functioning and structure of kidney. RPC’s are called as renal progenitor cells that are vital stem cells obtained from the kidney of a self donor. The researcher’s team from Tehran University of medical sciences conducted this study. During the research, scientists categorized rats into three groups. Out of these three, two groups were allowed to develop an induced pyelonephritis in the right kidney. It is a type of urinary infection that has reached the kidney or it is an infection of upper urinary tract. The third group of rat was not induced with any disease.

The renal progenitor cells were derived from the left kidney of diseased animals and were injected into the right kidney after an interval of six days. Two weeks later it was found out that tubular atrophy was reduced. After an interval of four weeks, fibrosis was reduced to a great extent and then after sixty days, the integrity of right renal tissue experienced a spectacular improvement. According to Dr Abdol-Mohammad Kajbafzadeh, the study of RPC transplant demonstrated the benefits of the disease. The disease pyelonephritis is a chronic infection that is responsible for the end stage of this renal disease.

These progenitor cells have functioning similar to that of stem cells extracted from menstrual blood storage or human embryos. Kajbafzadeh proposed that the growth of kidney was because of the regeneration of the functional tissue after cellular transplant. After the study, the researchers came to the conclusion that these kidney stem cells might be the right source for transplantation rather than those derived after isolate menstrual blood. It is because of their inborn property of organ specific differentiation and also their ability of modulation of the tissue that develops the risk of nephropathies.

The conclusion of the research given by the scientists was that renal fibrosis was the one and only path leading to end stage of kidney disease. So, the improvement of the fibrosis could serve to be a major relief. The study is however, the first study that has explained the enhanced functioning of renal tract after cellular transplantation. Nowadays, the number of people suffering from kidney disease is increasing at a high rate and thus this study can be called a major achievement for medical science. In addition, stem cells in menstrual blood or adult tissues can be used to replace the damaged organs and tissues due to their power of regeneration into such organs.